10 Best Bed Bug Spray of 2022

Top 10 Best Bed Bug Spray: Editor Recommended

The 10 Best Bed Bug Spray Review:

1. Ortho Home Defense Max Bed Bug

Defense Max Bed Bug

Ortho Home Defense Max Bed Bug, Flea & Tick Killer is the second step in a bed bug solution system. This spray kills even the toughest bed bugs (pyrethroid-resistant bed bugs) and their eggs.

Use it as a spot treatment to kill the bed bugs you see and in the places where they hide: Around bed frames, mattress seams/tufts/folds, and baseboards. It also kills fleas and ticks in your home. You can use Ortho Home Defense Max Bed Bug, Flea & Killer indoors with confidence.

Highlighted Features:

  • Use Ortho Home Defense Max Bed Bug, Flea & Tick Killer to kill bed bugs, bed bug eggs, fleas, and ticks
  • Use spray as a spot treatment around bed frames, mattress seams/tufts/folds, and baseboards
  • Kills even the toughest bed bugs (pyrethroid-resistant bed bugs)
  • Second step of a 3-step bed bug solution system
  • The continuous spray Comfort Wand easily gets into hard-to-reach areas

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2. Hot Shot Bed Bug Home Insect Killer

Bed Bug Home Insect Killer

Between the carpool and the couch cushions, you’re the CEO of the home front. Take care of your family – and take care of business, no matter where household pests rear their ugly heads. Show bugs who’s boss with Hot Shot insecticides. They’re your weapon of choice, giving you the clear advantage within your walls and at the bank.

Hot Shot Bed Bug Killer With Egg Kill kills bed bugs and bed bug eggs by contact and also offers control of fleas and dust mites. This non-staining, no odor formula can be used for spot treatment of mattress tufts, folds, vent holes and seams. To use this product, spray intended use areas until damp, but do not saturate. Inspect the area and apply every two weeks while bed bugs are present. This product is for indoor use only.

Do not treat pets with this product. People and pets should not be allowed in treated areas until the spray has dried. Treating bed bugs as part of a cycle is key to gaining control. For best results, use this product as part of a comprehensive bed bug treatment plan. When creepy bugs attempt to pass, save the day with Hot Shot insecticides.

Highlighted Features:

  • Hot Shot Bed Bug Killer With Egg Kill kills bed bugs and bed bug eggs, adult and pre-adult (larvae) fleas and dust mites.
  • Spot treat mattress tufts, folds, vent holes, buttons, creases, indentations and seams – do not use on pets.
  • This non-staining formula leaves no odor.
  • Spray intended use areas until damp, but do not saturate – inspect the area and apply every two weeks while bed bugs are present.
  • For best results, use this product as part of a comprehensive bed bug treatment plan — treating bed bugs as part of a cycle is key to gaining control.

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3. HARRIS Bed Bug and Egg Killer

Bed Bug and Egg Killer

Harris is America’s oldest EPA-registered company. With more than 100 products, the company provides solutions to treat everything from roaches and bed bugs to scorpions and stink bugs. Harris helps customers find easy and economical solutions to pest problems through helpful labeling, instructive videos and personal advice.

Highlighted Features:

  • Kills even the toughest “pyrethroid resistant” bed bugs and eggs that have built up a resistance to traditional pesticides
  • Knocks down bed bugs fast when sprayed directly
  • Approved for use in homes with people and pets by the Environmental Protection Agency (No. 1021-2597-3). Always follow label directions
  • Continues to kill bed bugs for up to 16 weeks after initial application
  • Odorless and non-staining formula will not cause damage to fabrics when used according to label directions

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4. Hot Shot 96442 HG-96442 1 Gallon Ready-to-Use Bed Bug Home Insect Killer

Gallon Ready-to-Use Bed Bug Home Insect Killer

No matter where your pest problem rears its ugly head, Hot Shot insecticides are the answer to what’s bugging you. Hot Shot insecticides offer a complete lineup of indoor and outdoor solutions to keep unwanted pests out of your home, and out of your life. Hot Shot Bed Bug Killer With Egg Kill kills bed bugs and bed bug eggs by contact. This product also kills fleas and dust mites.

The non-staining, no odor formula is for spot treatment of mattress tufts, folds, vent holes and seams. To use this product, spray intended use areas until damp. Do not saturate. Inspect the area and apply every two weeks while bed bugs are present. This product is for indoor use only. Do not treat pets with this product. People and pets should not be allowed in treated areas until the spray has dried. For best results, use this product as part of a comprehensive bed bug treatment plan.

Highlighted Features:

  • Spray intended use areas until damp
  • Do not saturate
  • Inspect area and apply every two weeks while bed bugs are present
  • Hot Shot Bed Bug Killer With Egg Kill kills bed bugs and bed bug eggs, adult and pre-adult (larvae) fleas and dust mites
  • Spot treat mattress tufts, folds, vent holes, buttons, creases, indentations and seams

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5. Bed Bug Killer by EcoRaider 16 oz

Bed Bug Killer by EcoRaider

According to the Rutgers University independent study published in the Journal of Economic Entomology, after testing 12 products, EcoRaider was the only natural product that achieved 100% mortality of bed bugs. In that same study, EcoRaider was also the most effective product of all in eliminating bed bug eggs.

EcoRaider not only eliminates bed bugs fast and thoroughly on contact, it provides an extended dry residual for two weeks post treatment. Studies have shown that EcoRaider’s two-week aged dry residual is still 97% effective in eliminating bed bugs! Another published university study demonstrated that EcoRaider outperforms most top grade professional products.

Highlighted Features:

  • Journal of economic entomology published university study confirmed that EcoRaider is the only natural product that kills bed bugs with 100 percent efficacy
  • field tested by research entomologists for eradicating bed bug infestations in public housing buildings and recommend for sensitive environment
  • Kills bed bug adults and nymphs fast on contact with 100% efficacy, kills bed bugs that are resistant to traditional pesticides. Proven highest performance in eliminating bed bug eggs
  • University study shows EcoRaider residual provides extended protection for two weeks on bed bugs even after dried
  • certified USDA BioBased insecticide, dermatologically safe; child and pet friendly; safe to use directly on mattress and box springs.

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6. MGK 1852 Crossfire Concentrate 13oz Insecticide

Crossfire Concentrate 13oz Insecticide

Crossfire is the newest formulation by industry leader MGK developed specifically for bedbugs. It combines 2 active ingredients (cloth I an ID in – 4% & metofluthrin – 0.1%) Plus a synergistic PbO (peperoni Butoxide – 10%). These active ingredients combine to penetrate the bed bug’s exoskeleton & then it attacks their central nervous system.

Metofluthrin is a fast acting insecticide that kills bedbugs within Min, & cloth I an ID in leaves a long lasting residual. Crossfire is formulated to kill parathyroid-resistant bed bug strains at all life stages, including eggs.

Easy to mix – one 13 oz bottle makes 1 gallon of finished product residual control begins working within Min of exposure approved for direct application onto mattresses quick knockdown & kill non-repellent non-staining kills parathyroid-resistant bed bugs kills all bed bug life stages by contact & prevents bed bug egg hatch for use in residential, institutional & commercial facilities pests controlled: bed bugs at all life stages – eggs, nymphs, & adults always read & follow label Directions when using any product.

Highlighted Features:

  • Crossfire is formulated to kill parathyroid resistant bed bug strains at all life stages, including eggs.
  • Quick knockdown and kill, residual control begins working within minutes of exposure
  • Approved For direct application onto mattresses
  • Easy to mix, one 13 oz bottle makes 1 gallon of finished product
  • Can not be shipped to new York

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7. Raid Bed Bug Foaming Spray

Bed Bug Foaming Spray

Raid Bed Bug Foaming Spray kills bed bugs and their eggs. Foam expands into hard-to-reach places, and it is easy to see where you sprayed. Defend your home against bed bugs for up to 4 weeks.

Highlighted Features:

  • Kills bed bugs & their eggs. Kills by contact
  • Kills bed bugs on surfaces for up to 4 weeks
  • Foam expands into hard to reach places, and is easy to see where you sprayed
  • Foam expands into hard to reach places, and is easy to see where you sprayed
  • Foam expands into hard to reach places, and is easy to see where you sprayed

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8. HARRIS Black Label Bed Bug Killer

Black Label Bed Bug Killer

Harris is America’s oldest EPA-registered company. With more than 100 products, the company provides solutions to treat everything from roaches and bed bugs to scorpions and stink bugs. Harris helps customers find easy and economical solutions to pest problems through helpful labeling, instructive videos and personal advice.

Highlighted Features:

  • Kills even the toughest “pyrethroid resistant” bed bugs and eggs that have built up a resistant to traditional pesticides
  • Knocks down bed bugs fast when sprayed directly
  • Approved for use in homes with people and pets by the Environmental Protection Agency (No. 1021-2597-3). Always follow label directions
  • Continues to kill bed bugs for up to 16 weeks after initial application
  • Odorless and non-staining formula will not cause damage to fabrics when used according to label directions

Buy on Amazon

9. EcoRaider Natural Bed Bug Killer 1 Gallon

Natural Bed Bug Killer

EcoRaider not only eliminates bed bugs fast and thoroughly on contact, it provides an extended dry residual for two weeks post treatment. Studies have shown that EcoRaider’s two-week aged dry residual is still 97% effective in eliminating bed bugs! Another published university study demonstrated that EcoRaider outperforms most top grade professional products.

Highlighted Features:

  • Entomological Society of America’s journal publication confirmed that EcoRaider is the only natural product that kills bed bugs with 100% efficacy
  • field tested by research entomologists for eradicating bed bug infestations in public housing buildings and recommend for sensitive environment.
  • Kills adults, nymphs fast on contact with 100% efficacy, kills bed bugs that are resistant to traditional pesticides. Highest performance in eliminating bed bug eggs
  • University study shows EcoRaider residual provides extended protection for two weeks on bed bugs even after dried.
  • Dermatologically safe; child and pet friendly; safe to use directly on mattress and box springs.

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10. Bedlam Plus Bed Bug Aerosol

Plus Bed Bug Aerosol

Bedlam insecticide Aerosol kills & Controls bed bugs, lice & dust mites. Labeled for use in the toughest hiding places including headboards, box Springs & mattresses, Bedlam is a water-based product that won’t stain water-safe fabrics & is non-irritating to humans & animals. Bedlam is the first name in bed bug control.

Highlighted Features:

  • Kills bed bugs and their eggs
  • Two week residual on wood, ceramic surfaces and carpet
  • Reduces bed bug egg hatch in both susceptible and some resistant strains of bed bugs
  • For surface spray application on mattresses, wood furniture and carpet
  • Water-based product won’t stain water-safe fabrics and surfaces
  • For use in non-food areas of homes, hotels, apartments, nursing homes, schools and other commercial sites

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